What are the subunits of RNA polymerase (RNAP)?

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Study for the UCF PCB4524 Molecular Biology II Exam. Prepare with flashcards and multiple choice questions, each with hints and explanations. Gear up for success!

RNA polymerase (RNAP) is a crucial enzyme involved in the transcription process, where DNA is converted into RNA. The structure of bacterial RNA polymerase is composed of several subunits that come together to form the holoenzyme necessary for transcription.

The correct composition of the bacterial RNA polymerase includes two alpha (α) subunits, one beta (β) subunit, one beta prime (β') subunit, and one omega (ω) subunit. These subunits combine to form a core enzyme essential for binding to the DNA template and synthesizing RNA.

The specific organization of these subunits is important for the enzyme’s function. The two alpha subunits contribute to the assembly of the enzyme and interaction with regulatory factors, while the beta and beta prime subunits create the catalytic site. The omega subunit helps in maintaining the structural stability of the core enzyme.

In contrast, the other options listed do not represent the correct subunits found in RNA polymerase. For example, options referencing numbers or letters not associated with the established nomenclature of RNA polymerase subunits do not align with the scientifically accepted structure of the enzyme. Thus, the option reflecting the traditional subunits accurately describes the composition and functionality of RNA polymerase.