What is the function of helicase during DNA replication?

The function of helicase during DNA replication is to unwind the DNA double helix. This enzyme plays a critical role in separating the two strands of the DNA molecule, allowing the replication machinery access to the single-stranded templates needed to synthesize new DNA strands. By unwinding the DNA, helicase creates a replication fork, which is essential for the progression of replication.

Without helicase, the DNA strands would remain coiled together, making it impossible for other enzymes involved in replication, such as DNA polymerases, to synthesize new strands. Its activity is vital for facilitating the overall process of DNA replication, ensuring that each strand can be copied accurately and efficiently.