Which of the following is NOT one of the GTFs required by RNAP2?

RNA polymerase II (RNAP2) requires several general transcription factors (GTFs) to initiate transcription effectively. The identified GTFs play critical roles in the formation of the pre-initiation complex needed for transcription to commence.

TFIIA is essential as it stabilizes the binding of TFIID to the promoter region and helps in the recruitment of RNAP2. TFIIB is important for the recruitment of RNAP2 to the transcription start site and aids in the positioning of the polymerase at the promoter. TFIIF is involved in bridging interactions between RNAP2 and the upstream factors, helping in the proper assembly of the transcription machinery.

On the other hand, TFIIG is not one of the primary general transcription factors associated directly with RNAP2 initiation. While TFIIG is associated with RNAP2 and is involved in the transcription process, it does not play a direct role in the initial assembly of the transcription machinery at the promoter compared to the other factors mentioned. This is why TFIIG is considered the option that is NOT required in the initial context of forming the pre-initiation complex for RNAP2.